Skip to content
Atlas Research Compounds

GHK-Cu: Animal studies

Preclinical animal models and the boundaries on translating their results.

7 verified studies

Search all studies →
Grade CAnimal study2024Indexed abstract extracted

The glycyl-l-histidyl-l-lysine-Cu(2+) tripeptide complex attenuates lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 6

A mouse silicosis model with complementary RAW264.7 macrophage experiments and target investigation involving peroxiredoxin 6.

Journal
Redox Biology
Evidence context
Preclinical or narrative synthesis
Review study record →
Grade CAnimal study2022Indexed abstract extracted

Biomimetic Hydrogel Scaffolds with Copper Peptide-Functionalized RADA16 Nanofiber Improve Wound Healing in Diabetes

A functionalized RADA16 hydrogel study combining endothelial-cell assays with wound-healing experiments in healthy and diabetic mice.

Journal
Macromolecular Bioscience
Evidence context
Preclinical or narrative synthesis
Review study record →
Grade CAnimal study2020Indexed abstract extracted

Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways

A bleomycin-induced pulmonary-fibrosis study in C57BL/6J mice examining histology, inflammation, collagen, EMT, and signaling pathways.

Journal
Life Sciences
Evidence context
Preclinical or narrative synthesis
Review study record →
Grade CAnimal study2016Indexed abstract extracted

The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice

A combined RAW264.7 macrophage and mouse lipopolysaccharide acute-lung-injury investigation.

Journal
Oncotarget
Evidence context
Preclinical or narrative synthesis
Review study record →
Grade CAnimal study1993Indexed abstract extracted

In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds

A rat wound-chamber experiment measuring matrix composition and collagen-related messenger RNA after local GHK-Cu exposure.

Journal
The Journal of Clinical Investigation
Evidence context
Preclinical or narrative synthesis
Review study record →
Grade CAnimal study2018PubMed metadata verified

Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.

Verified PubMed record for GHK-Cu: Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.

Journal
International journal of molecular sciences
Evidence context
Preclinical or narrative synthesis
Review study record →
Grade CAnimal study2015PubMed metadata verified

Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction.

Verified PubMed record for GHK-Cu: Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction.

Journal
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Evidence context
Preclinical or narrative synthesis
Review study record →

Model inventory

The glycyl-l-histidyl-l-lysine-Cu(2+) tripeptide complex attenuates lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 6
Mouse
Biomimetic Hydrogel Scaffolds with Copper Peptide-Functionalized RADA16 Nanofiber Improve Wound Healing in Diabetes
Mouse
Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways
Mouse
The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice
Mouse
In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds
Rat
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.
Rat
Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction.
Rat

Related topic hubs