Verified publication
The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice
A combined RAW264.7 macrophage and mouse lipopolysaccharide acute-lung-injury investigation.
Indexed abstract extractedQuality: LowLow confidence
Study metadata
- Journal
- Oncotarget
- Publication year
- 2016
- Study type
- Animal study
- Species
- Mouse
- Evidence grade
- Grade C
- Extraction depth
- Indexed abstract extracted
- Study quality
- Low
- Confidence
- Low confidence
- Sample size
- Not stated in indexed abstract
Structured extraction
- Population
- Mouse model; strain and model details require article-level extraction.
- Intervention
- Animal-model exposure details require abstract or full-text extraction before use.
- Comparator
- Not stated or not fully extracted from the indexed abstract.
- Duration
- Not stated or not fully extracted from the indexed abstract.
- Primary endpoint
- Primary animal-model endpoint not fully extracted.
- Secondary endpoints
- No secondary endpoints extracted.
- Funding source
- Not stated in the indexed abstract.
Findings and extraction notes
- The abstract reports lower oxidative and inflammatory measures and less histological lung injury after GHK-Cu exposure.
Limitations
- The work is preclinical and combines cell and mouse-model evidence.
- The abstract does not state animal or cell-replicate counts.