Bioregulatory peptides
Pinealon
A short synthetic tripeptide studied in bioregulation models.
Evidence score1/5
Preclinical foundation
- Evidence
- Preclinical
- Status
- Published
Topic authority hub
Healthy Aging
Aging-related publications, geroscience mechanisms, tissue maintenance models, and conservative interpretation boundaries.
Research frame
Healthy-aging content can easily become overclaiming. Atlas keeps aging-related pages tied to verified publications, compound profile evidence ratings, and explicit limitations.
This hub connects Pinealon, GHK-Cu, MOTS-C, SS-31, and NAD+ without converting mechanistic aging biology into outcome promises.
Featured compounds
Repair & matrix
GHK-Cu
A copper-binding tripeptide complex studied in matrix biology.
Evidence score3/5
Developing clinical evidence
- Evidence
- Mixed translational
- Status
- Published
Metabolic signaling
MOTS-C
A mitochondrial-derived peptide studied in metabolic signaling.
Evidence score2/5
Early human evidence
- Evidence
- Preclinical
- Status
- Published
Metabolic signaling
SS-31
A mitochondria-targeted tetrapeptide indexed in the literature as elamipretide and MTP-131.
Evidence score3/5
Developing clinical evidence
- Evidence
- Mixed translational
- Status
- Published
Metabolic signaling
NAD+
A ubiquitous redox cofactor and substrate in cellular metabolism.
Evidence score5/5
Established evidence base
- Evidence
- Established biochemical
- Status
- Published
Featured studies
Grade CReview2020Indexed abstract extracted
EDR Peptide: Possible Mechanism of Gene Expression and Protein Synthesis Regulation Involved in the Pathogenesis of Alzheimer's Disease
A narrative review of proposed EDR peptide effects on gene expression, protein synthesis, apoptosis, antioxidant systems, and neuronal models.
- Journal
- Molecules (Basel, Switzerland)
- Evidence context
- Preclinical or narrative synthesis
Grade BReview2020PubMed metadata verified
The potential of GHK as an anti-aging peptide.
Verified PubMed record for GHK-Cu: The potential of GHK as an anti-aging peptide.
- Journal
- Aging pathobiology and therapeutics
- Evidence context
- Human comparative or observational evidence
Grade BHuman observational study2022PubMed metadata verified
MOTS-C, the most recent mitochondrial-derived peptide in human aging and age-related diseases.
Verified PubMed record for MOTS-C: MOTS-C, the most recent mitochondrial-derived peptide in human aging and age-related diseases.
- Journal
- International journal of molecular sciences
- Evidence context
- Human comparative or observational evidence
Comparisons
Pinealon vs. CortagenTwo short peptide bioregulators whose proposed tissue associations require careful separation from independently replicated target-level evidence.MOTS-C vs. SS-31A structured research comparison between MOTS-C and SS-31 across compound identity, research category, evidence maturity, and interpretation boundaries.MOTS-C vs. NAD+A structured research comparison between MOTS-C and NAD+ across compound identity, research category, evidence maturity, and interpretation boundaries.
Authority articles
Healthy aging
Pinealon Review
Pinealon is best understood as a short-peptide bioregulator research cluster with limited independent replication.
Peptide research
GHK-Cu Research Overview
GHK-Cu has a deep matrix-biology footprint, but formulation and model boundaries determine what can be claimed.
Mitochondrial health
MOTS-C Research Overview
MOTS-C is an authority bridge between mitochondrial-derived peptides, metabolism, aging, and redox biology.
Mitochondrial health
SS-31 Research Overview
SS-31 has enough translational literature to deserve its own hub role, but the evidence is still endpoint- and disease-context dependent.