Neuropeptides
Semax
A synthetic heptapeptide derived from an ACTH fragment.
Evidence score2/5
Early human evidence
- Evidence
- Early clinical
- Status
- Published
Topic authority hub
Cognition
Neural signaling, stress response, memory models, and the gap between mechanistic and human evidence.
Research frame
Cognition research spans imaging, behavior, molecular signaling, and disease-specific models. A positive result in one layer does not automatically predict a meaningful outcome in another.
This hub emphasizes study design and species so that human observations remain visibly separate from animal and cell findings.
Featured compounds
Neuropeptides
Selank
A synthetic tuftsin-related heptapeptide.
Evidence score2/5
Early human evidence
- Evidence
- Early clinical
- Status
- Published
Bioregulatory peptides
Pinealon
A short synthetic tripeptide studied in bioregulation models.
Evidence score1/5
Preclinical foundation
- Evidence
- Preclinical
- Status
- Published
Neuropeptides
DSIP
A nonapeptide historically investigated in sleep and stress research.
Evidence score2/5
Early human evidence
- Evidence
- Mixed translational
- Status
- Published
Featured studies
Grade BHuman observational study2018Indexed abstract extracted
Effects of Semax on the Default Mode Network of the Brain
A resting-state fMRI study comparing 14 Semax-exposed and 10 placebo-exposed healthy volunteers.
- Journal
- Bulletin of Experimental Biology and Medicine
- Evidence context
- Human comparative or observational evidence
Grade BHuman observational study2014Indexed abstract extracted
A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders
A comparative study of Selank and phenazepam in 60 patients with phobic-anxiety and somatoform disorders.
- Journal
- Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
- Evidence context
- Human comparative or observational evidence
Grade CReview2020Indexed abstract extracted
EDR Peptide: Possible Mechanism of Gene Expression and Protein Synthesis Regulation Involved in the Pathogenesis of Alzheimer's Disease
A narrative review of proposed EDR peptide effects on gene expression, protein synthesis, apoptosis, antioxidant systems, and neuronal models.
- Journal
- Molecules (Basel, Switzerland)
- Evidence context
- Preclinical or narrative synthesis
Comparisons
Semax vs. SelankTwo synthetic neuropeptides with different source motifs and overlapping but non-equivalent cognition and stress-response research contexts.Pinealon vs. CortagenTwo short peptide bioregulators whose proposed tissue associations require careful separation from independently replicated target-level evidence.
Authority articles
Neuroprotection
What Is Semax?
Semax has a wider publication footprint than many catalog neuropeptides, but the literature still separates mechanistic models from human inference.
Cognition
What Is Selank?
Selank’s strongest catalog value is as a mapped research cluster, not as a single simplified mechanism claim.
Healthy aging
Pinealon Review
Pinealon is best understood as a short-peptide bioregulator research cluster with limited independent replication.