Verified publication
Effects of Semax on the Default Mode Network of the Brain
A resting-state fMRI study comparing 14 Semax-exposed and 10 placebo-exposed healthy volunteers.
Indexed abstract extractedQuality: ModerateModerate confidence
Study metadata
- Journal
- Bulletin of Experimental Biology and Medicine
- Publication year
- 2018
- Study type
- Human observational study
- Species
- Human
- Evidence grade
- Grade B
- Extraction depth
- Indexed abstract extracted
- Study quality
- Moderate
- Confidence
- Moderate confidence
- Sample size
- 24
Structured extraction
- Population
- Human participants; population details require article-level extraction.
- Intervention
- Exposure or intervention details require abstract or full-text extraction before use.
- Comparator
- Not stated or not fully extracted from the indexed abstract.
- Duration
- Not stated or not fully extracted from the indexed abstract.
- Primary endpoint
- Primary outcome or association endpoint not fully extracted.
- Secondary endpoints
- No secondary endpoints extracted.
- Funding source
- Not stated in the indexed abstract.
Findings and extraction notes
- The Semax group showed a larger rostral default-mode-network subcomponent than the placebo group in the reported imaging analysis.
Limitations
- The sample was small and the abstract does not report randomized allocation.
- The imaging endpoint does not establish a clinical outcome.