Verified publication
The efficacy of Semax in the treatment of patients at different stages of ischemic stroke
A rehabilitation-stage comparison that followed 110 people after ischemic stroke and assessed plasma BDNF, motor performance, and Barthel index scores.
Indexed abstract extractedQuality: ModerateModerate confidence
Study metadata
- Journal
- Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
- Publication year
- 2018
- Study type
- Human observational study
- Species
- Human
- Evidence grade
- Grade B
- Extraction depth
- Indexed abstract extracted
- Study quality
- Moderate
- Confidence
- Moderate confidence
- Sample size
- 110
Structured extraction
- Population
- Human participants; population details require article-level extraction.
- Intervention
- Exposure or intervention details require abstract or full-text extraction before use.
- Comparator
- Not stated or not fully extracted from the indexed abstract.
- Duration
- Not stated or not fully extracted from the indexed abstract.
- Primary endpoint
- Primary outcome or association endpoint not fully extracted.
- Secondary endpoints
- No secondary endpoints extracted.
- Funding source
- Not stated in the indexed abstract.
Findings and extraction notes
- The indexed abstract reports higher plasma BDNF and faster functional recovery in Semax-treated subgroups, alongside an independent association with earlier rehabilitation.
Limitations
- The abstract describes treatment subgroups but does not establish randomized allocation or blinding.
- The publication is in Russian and the indexed English abstract provides limited methodological detail.