Grade ASystematic review and meta-analysis·2025Indexed abstract extracted
Thymosin alpha 1 alleviates inflammation and prevents infection in patients with severe acute pancreatitis through immune regulation: a systematic review and meta-analysis
A systematic review and meta-analysis of five randomized studies in severe acute pancreatitis.
- Journal
- Frontiers in Immunology
- Evidence context
- High-level synthesis or controlled evidence
Review study record →Grade ASystematic review and meta-analysis·2023Indexed abstract extracted
The efficacy of thymosin alpha-1 therapy in moderate to critical COVID-19 patients: a systematic review, meta-analysis, and meta-regression
A synthesis of eight studies evaluating thymosin alpha-1 in moderate-to-critical COVID-19.
- Journal
- Inflammopharmacology
- Evidence context
- High-level synthesis or controlled evidence
Review study record →Grade BHuman observational study·2021Indexed abstract extracted
Efficacy of Thymosin Alpha 1 in the Treatment of COVID-19: A Multicenter Cohort Study
A five-hospital cohort study comparing 306 thymosin alpha-1 recipients with 1,976 non-recipients during early COVID-19 care.
- Journal
- Frontiers in Immunology
- Evidence context
- Human comparative or observational evidence
Review study record →Grade BHuman observational study·2021Indexed abstract extracted
Thymosin Alpha-1 Has no Beneficial Effect on Restoring CD4+ and CD8+ T Lymphocyte Counts in COVID-19 Patients
A retrospective study comparing lymphocyte trajectories and viral clearance in 275 hospitalized COVID-19 patients.
- Journal
- Frontiers in Immunology
- Evidence context
- Human comparative or observational evidence
Review study record →Grade CIn vitro study·2021Indexed abstract extracted
Thymosin Alpha 1 Mitigates Cytokine Storm in Blood Cells From Coronavirus Disease 2019 Patients
An ex vivo analysis of inflammatory signaling in blood cells from people with COVID-19, including CD8-positive T-cell responses.
- Journal
- Open Forum Infectious Diseases
- Evidence context
- Preclinical or narrative synthesis
Review study record →Grade ASystematic review and meta-analysis·2020Indexed abstract extracted
The clinical efficacy and adverse effects of Entecavir plus Thymosin alpha-1 combination therapy versus Entecavir Monotherapy in HBV-related cirrhosis: a systematic review and meta-analysis
A systematic review and meta-analysis of seven randomized studies comparing entecavir plus thymosin alpha-1 with entecavir alone.
- Journal
- BMC Gastroenterology
- Evidence context
- High-level synthesis or controlled evidence
Review study record →Grade DReview·2001PubMed metadata verified
Thymosin alpha-1.
Verified PubMed record for Thymosin Alpha 1: Thymosin alpha-1.
- Journal
- American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
- Evidence context
- Metadata-only, mechanistic, or limited evidence
Review study record →Grade DReview·2025PubMed metadata verified
Aging and Thymosin Alpha-1.
Verified PubMed record for Thymosin Alpha 1: Aging and Thymosin Alpha-1.
- Journal
- International journal of molecular sciences
- Evidence context
- Metadata-only, mechanistic, or limited evidence
Review study record →Grade AHuman randomized trial·2023PubMed metadata verified
A Pilot Trial of Thymalfasin (Thymosin-α-1) to Treat Hospitalized Patients With Hypoxemia and Lymphocytopenia Due to Coronavirus Disease 2019 Infection.
Verified PubMed record for Thymosin Alpha 1: A Pilot Trial of Thymalfasin (Thymosin-α-1) to Treat Hospitalized Patients With Hypoxemia and Lymphocytopenia Due to Coronavirus Disease 2019 Infection.
- Journal
- The Journal of infectious diseases
- Evidence context
- High-level synthesis or controlled evidence
Review study record →Grade DReview·2015PubMed metadata verified
Thymosin alpha-1 treatment in chronic hepatitis B.
Verified PubMed record for Thymosin Alpha 1: Thymosin alpha-1 treatment in chronic hepatitis B.
- Journal
- Expert opinion on biological therapy
- Evidence context
- Metadata-only, mechanistic, or limited evidence
Review study record →Grade AHuman randomized trial·2025PubMed metadata verified
The efficacy and safety of thymosin α1 for sepsis (TESTS): multicentre, double-blinded, randomised, placebo-controlled, phase 3 trial.
Verified PubMed record for Thymosin Alpha 1: The efficacy and safety of thymosin α1 for sepsis (TESTS): multicentre, double-blinded, randomised, placebo-controlled, phase 3 trial.
- Journal
- BMJ (Clinical research ed.)
- Evidence context
- High-level synthesis or controlled evidence
Review study record →Grade BReview·2017PubMed metadata verified
Thymosin alpha 1 and HIV-1: recent advances and future perspectives.
Verified PubMed record for Thymosin Alpha 1: Thymosin alpha 1 and HIV-1: recent advances and future perspectives.
- Journal
- Future microbiology
- Evidence context
- Human comparative or observational evidence
Review study record →Grade BHuman observational study·2018PubMed metadata verified
Thymosin alpha 1 treatment for patients with sepsis.
Verified PubMed record for Thymosin Alpha 1: Thymosin alpha 1 treatment for patients with sepsis.
- Journal
- Expert opinion on biological therapy
- Evidence context
- Human comparative or observational evidence
Review study record →Grade BHuman observational study·2018PubMed metadata verified
Serum thymosin alpha 1 levels in normal and pathological conditions.
Verified PubMed record for Thymosin Alpha 1: Serum thymosin alpha 1 levels in normal and pathological conditions.
- Journal
- Expert opinion on biological therapy
- Evidence context
- Human comparative or observational evidence
Review study record →Grade BReview·2023PubMed metadata verified
Thymosin α-1 in cancer therapy: Immunoregulation and potential applications.
Verified PubMed record for Thymosin Alpha 1: Thymosin α-1 in cancer therapy: Immunoregulation and potential applications.
- Journal
- International immunopharmacology
- Evidence context
- Human comparative or observational evidence
Review study record →Grade BHuman observational study·2004PubMed metadata verified
Thymalfasin (thymosin-alpha 1) therapy in patients with chronic hepatitis B.
Verified PubMed record for Thymosin Alpha 1: Thymalfasin (thymosin-alpha 1) therapy in patients with chronic hepatitis B.
- Journal
- Journal of gastroenterology and hepatology
- Evidence context
- Human comparative or observational evidence
Review study record →Grade DReview·2016PubMed metadata verified
Immune Modulation with Thymosin Alpha 1 Treatment.
Verified PubMed record for Thymosin Alpha 1: Immune Modulation with Thymosin Alpha 1 Treatment.
- Journal
- Vitamins and hormones
- Evidence context
- Metadata-only, mechanistic, or limited evidence
Review study record →Grade CIn vitro study·2022PubMed metadata verified
Thymosin α-1 Reverses M2 Polarization of Tumor-Associated Macrophages during Efferocytosis.
Verified PubMed record for Thymosin Alpha 1: Thymosin α-1 Reverses M2 Polarization of Tumor-Associated Macrophages during Efferocytosis.
- Journal
- Cancer research
- Evidence context
- Preclinical or narrative synthesis
Review study record →Grade BReview·2015PubMed metadata verified
Historical review of thymosin α 1 in infectious diseases.
Verified PubMed record for Thymosin Alpha 1: Historical review of thymosin α 1 in infectious diseases.
- Journal
- Expert opinion on biological therapy
- Evidence context
- Human comparative or observational evidence
Review study record →Grade BReview·1994PubMed metadata verified
Clinical applications of thymosin alpha-1.
Verified PubMed record for Thymosin Alpha 1: Clinical applications of thymosin alpha-1.
- Journal
- Cancer investigation
- Evidence context
- Human comparative or observational evidence
Review study record →