Verified publication
Pinealon protects the rat offspring from prenatal hyperhomocysteinemia
A prenatal methionine-loading rat model examining offspring learning, spatial orientation, oxidative stress, and cerebellar-neuron viability.
Indexed abstract extractedQuality: LowLow confidence
Study metadata
- Journal
- International Journal of Clinical and Experimental Medicine
- Publication year
- 2012
- Study type
- Animal study
- Species
- Rat
- Evidence grade
- Grade C
- Extraction depth
- Indexed abstract extracted
- Study quality
- Low
- Confidence
- Low confidence
- Sample size
- Not stated in indexed abstract
Structured extraction
- Population
- Rat model; strain and model details require article-level extraction.
- Intervention
- Animal-model exposure details require abstract or full-text extraction before use.
- Comparator
- Not stated or not fully extracted from the indexed abstract.
- Duration
- Not stated or not fully extracted from the indexed abstract.
- Primary endpoint
- Primary animal-model endpoint not fully extracted.
- Secondary endpoints
- No secondary endpoints extracted.
- Funding source
- Not stated in the indexed abstract.
Findings and extraction notes
- The abstract reports improved spatial learning measures and fewer oxidative-stress and necrotic-cell signals in offspring from Pinealon-treated dams.
Limitations
- Prenatal animal exposure is a specialized model with uncertain human relevance.
- No DOI or animal count is indexed in the PubMed record.