Verified publication
Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats
An elevated-plus-maze study of individual and combined Selank and diazepam exposure in rats with and without chronic mild stress.
Indexed abstract extractedQuality: LowLow confidence
Study metadata
- Journal
- Behavioural Neurology
- Publication year
- 2017
- Study type
- Animal study
- Species
- Rat
- Evidence grade
- Grade C
- Extraction depth
- Indexed abstract extracted
- Study quality
- Low
- Confidence
- Low confidence
- Sample size
- Not stated in indexed abstract
Structured extraction
- Population
- Rat model; strain and model details require article-level extraction.
- Intervention
- Animal-model exposure details require abstract or full-text extraction before use.
- Comparator
- Not stated or not fully extracted from the indexed abstract.
- Duration
- Not stated or not fully extracted from the indexed abstract.
- Primary endpoint
- Primary animal-model endpoint not fully extracted.
- Secondary endpoints
- No secondary endpoints extracted.
- Funding source
- Not stated in the indexed abstract.
Findings and extraction notes
- The combined exposure produced the strongest reported reduction in anxiety measures under the study's chronic-stress condition.
Limitations
- Behavioral measures in a rat stress model do not establish treatment effects in people.
- The abstract does not state the number of animals.