Verified publication
GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration
A narrative review of GHK and GHK-Cu literature concerning matrix remodeling, wound models, cellular pathways, and skin-related applications.
Indexed abstract extractedQuality: ModerateModerate confidence
Study metadata
- Journal
- BioMed Research International
- Publication year
- 2015
- Study type
- Review
- Species
- Multiple or not applicable
- Evidence grade
- Grade C
- Extraction depth
- Indexed abstract extracted
- Study quality
- Moderate
- Confidence
- Moderate confidence
- Sample size
- Not stated in indexed abstract
Structured extraction
- Population
- Multiple, review-level, or not applicable population context.
- Intervention
- Review article; no single intervention arm is extracted.
- Comparator
- Not stated or not fully extracted from the indexed abstract.
- Duration
- Not stated or not fully extracted from the indexed abstract.
- Primary endpoint
- Synthesis scope rather than a primary endpoint.
- Secondary endpoints
- No secondary endpoints extracted.
- Funding source
- Not stated in the indexed abstract.
Findings and extraction notes
- The review summarizes reported effects on collagen, glycosaminoglycans, metalloproteinases, cell recruitment, and wound-related models.
Limitations
- This is a narrative review and includes heterogeneous experimental systems and application contexts.
- Review-level claims require confirmation against the underlying primary studies.
