Verified publication
Glycyl-l-histidyl-l-lysine prevents copper- and zinc-induced protein aggregation and central nervous system cell death in vitro
An in vitro investigation of GHK in copper- and zinc-associated protein aggregation, redox activity, inflammation, and cell-death models.
Indexed abstract extractedQuality: LowLow confidence
Study metadata
- Journal
- Metallomics : integrated biometal science
- Publication year
- 2024
- Study type
- In vitro study
- Species
- Cell or artificial model
- Evidence grade
- Grade D
- Extraction depth
- Indexed abstract extracted
- Study quality
- Low
- Confidence
- Low confidence
- Sample size
- Not stated in indexed abstract
Structured extraction
- Population
- Cell or artificial model; cell line and assay details require article-level extraction.
- Intervention
- In vitro exposure details require abstract or full-text extraction before use.
- Comparator
- Not stated or not fully extracted from the indexed abstract.
- Duration
- Not stated or not fully extracted from the indexed abstract.
- Primary endpoint
- Primary assay endpoint not fully extracted.
- Secondary endpoints
- No secondary endpoints extracted.
- Funding source
- Not stated in the indexed abstract.
Findings and extraction notes
- The abstract reports reduced metal redox activity, protein aggregation, and tested cell-death signals after GHK exposure.
Limitations
- The study uses in vitro systems and does not establish effects in animals or people.
- The work evaluates GHK rather than every possible GHK-Cu formulation.